7 Drug Interaction Chart

  • Alprazolam+CBD=Increased likelihood of unwanted side-effects, and decreaeses impact of Alprazolam due to Kratom being an inhibitor of CYP3A4 enzymes, which alprazolam needs to be able to be broken down and be absorbed.
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  • Alprazolam+GABA=Increased side-effect of dizziness, confusion, and poor concentration. GABA will potentiate the effects of Alprazolam, do NOT take together.
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  • Alprazolam+Kratom=In low doses, all strains of kratom run the risk of counteracting the effects of Xanax — preventing it from effectively managing symptoms. In higher doses, kratom has the opposite effect and could make the effects of Xanax too strong — potentially leading to side effects and overdose.
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  • Alprazolam+L-Tyrosine=No Known Interaction.
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  • Alprazolam+Mirtazapine=Causes intense sleepiness and drowsiness.
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  • Alprazolam+THC=Can cause worsened anxiety.
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  • CBD+GABA=Stress reduction, improved sleep, improved mood regulation, better pain management, and mucsle relaxation.
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  • CBD+Kratom=No direct interaction. CBD can potentiate Kratom due to CBD inhibiting enzymes that break down Kratom, leading to a longer-lasting effect.
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  • CBD+L-Tyrosine=Increase in energy.
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  • CBD+Mirtazapine=CBD inhibits the breakdown (metabolism) of Mirtazapine, so there is a risk of overdose-like symptoms when taken together with CBD. Also causes drowsiness.
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  • CBD+THC=CBD reduces unwanted effects of THC, such as paranoia and anxiety.
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  • GABA+CBD=CBD stops the inhibition of GABAergic interneurons, leading to feelings of anxiety and paranoia.
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  • GABA+Kratom=Little-to-no interaction. Reported restlessness.
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  • GABA+L-Tyrosine=May lessen anxiety.
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  • GABA+Mirtazapine=No Interaction. Mirtazapine doesn't affect GABA receptors.
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  • GABA+THC=Can cause worsened anxiety.
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  • Kratom+L-Tyrosine=L-Tyrosine slightly potentiates Kratom. May create tolerance.
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  • Kratom+Mirtazapine=Little reaction. Mirtazapine influences opiod receptors, may cause potentiation of Kratom.
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  • Kratom+THC=Mood elevation, pain relief, enhanced relaxation. Dizziness, sedation, nausea.
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  • L-Tyrosine+Mirtazapine=No Interaction.
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  • L-Tyrosine+THC=Should be avoided, as THC can have stimulant effects which may cause strain.
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  • Mirtazapine+THC=No Interaction
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